Agios Pharmaceuticals, Inc.

Agios Pharmaceuticals, Inc.

Healthcare

NASDAQ:AGIO · NASDAQ Global Select

Market Cap $1.75B Beta 0.59 P/E (TTM) -4.1
$29.46 +2.58%

+$0.74 today

52W Low $22.24High $46.00

Vol 1.14M · Avg 1.06M

EPS (TTM)-$7.19
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-34.6%

avg -27.4%

ROIC

-38.2%

avg -40.3%

ROA

-31.8%

avg -15.7%

Analysis

ROA is currently the strongest return metric at -31.8% versus its period average of -15.7%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Brian Goff

Chief Executive Officer & Director$1.45M57$191,104.000.32%

Krishnan Viswanadhan

Chief Strategy & Operations Officer$931,509.0047$10,282.000.02%

Sarah Gheuens

Chief Medical Officer and Head of Research & Development$887,232.0046$8,500.000.01%

Tsveta Milanova

Chief Commercial Officer$836,643.0048$46,829.000.08%

Cecilia Jones

Chief Financial Officer$791,835.0051$58,139.000.10%

James William Burns

Chief Legal Officer$780,510.0048$8,500.000.01%

Craig Thompson

Co-Founder$50,000.0073

Tak Wah Mak FRSC

Co-Founder$50,000.0080

Shin-San Su

Co-Founder$50,000.0070

Lewis Clayton Cantley

Co-Founder$50,000.0077

Steven Vickers

Vice President of Sales

T. J. Washburn

Vice President, Controller & Principal Accounting Officer44$868.00<0.01%

Clive Patience

Chief Technical Operations Officer62

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

55

$6.19M

Net Sentiment

$6.19M

Net selling

Most Active

Gheuens Sarah

12 transactions

DateInsiderTypeSharesPriceValue
Apr 2, 2026

Burns James William

Direct

Sell3.3K$34.71$113,848.80
Apr 2, 2026

Gheuens Sarah

Direct

Sell2.9K$34.71$102,047.40
Apr 2, 2026

Jones Cecilia

Direct

Sell3.1K$34.71$109,024.11
Apr 2, 2026

Milanova Tsveta

Direct

Sell3.3K$34.71$113,224.02
Apr 2, 2026

Viswanadhan Krishnan

Direct

Sell3.0K$34.71$102,706.89
Apr 2, 2026

Goff Brian

Direct

Sell6.6K$34.71$228,947.16
Apr 2, 2026

Goff Brian

Direct

Sell12.5K$34.71$432,903.12
Mar 5, 2026

Viswanadhan Krishnan

Direct

Sell3.0K$27.80$82,260.20
Mar 3, 2026

Washburn Theodore James Jr.

Direct

Sell5.3K$28.88$152,255.36
Mar 2, 2026

Goff Brian

Direct

Sell5.9K$28.96$171,385.28

1–10 of 55

Analysis

Insiders reported 0 buys worth $0.00 and 55 sells worth $6.19M over the last 12 months. That adds up to net selling of $6.19M. Gheuens Sarah was the most active insider with 12 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A6 analysts
RevenueN/AN/A+33.0%
+17.8% (15yr)7 analysts
Net IncomeN/AN/AN/A
N/A7 analysts
EBITN/AN/AN/A
N/A7 analysts

Analysis

Recent growth has been strongest in Revenue at +33.0% over three years. Forward estimates point to Revenue at +17.8% (15yr), giving you a quick check on whether expectations are accelerating or cooling.

Who manages AGIO?

Agios Pharmaceuticals, Inc. (AGIO) lists 13 active executives. The top listed executive is Craig Thompson, Co-Founder.

Are AGIO insiders buying or selling?

Recent insider activity shows net buying of $8.89M.

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