Axsome Therapeutics, Inc.

Axsome Therapeutics, Inc.

Healthcare

NASDAQ:AXSM · NASDAQ Global Market

Market Cap $13.13B Beta 0.60 P/E (TTM) -69.4
$255.17 +0.55%

+$1.40 today

52W Low $96.09High $257.93

Vol 0.44M · Avg 0.72M

EPS (TTM)-$3.68
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-207.5%

avg -508.8%

ROIC

-44.0%

avg -106.1%

ROA

-26.6%

avg -71.6%

Analysis

ROA is currently the strongest return metric at -26.6% versus its period average of -71.6%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Herriot Tabuteau

Founder, Chairman, Chief Executive Officer & President$1.92M58$99,330.000.19%

Mark L. Jacobson

Chief Operating Officer$1.06M43$30,389.000.06%

Nick Pizzie

Chief Financial Officer$974,594.0051$75,867.000.15%

Hunter Murdock

General Counsel & Secretary$960,636.0046$7,224.000.01%

Ari Maizel

Chief Commercial Officer$924,989.0047$23,710.000.05%

Darren Opland

Director of Corporate Communications

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

3

$200,466.30

Sells

49

$146.09M

Net Sentiment

$145.89M

Net selling

Most Active

TABUTEAU HERRIOT

17 transactions

DateInsiderTypeSharesPriceValue
Jun 11, 2026

JEFFS ROGER

Direct

Sell286$249.12$71,248.32
Jun 10, 2026

Mahony Susan

Direct

Sell300$246.18$73,854.00
Jun 10, 2026

JEFFS ROGER

Direct

Sell286$246.18$70,407.48
Jun 10, 2026

Coleman Mark

Direct

Sell643$249.00$160,107.00
Jun 9, 2026

Mahony Susan

Direct

Sell300$237.21$71,163.00
Jun 9, 2026

TABUTEAU HERRIOT

Direct

Sell49.7K$241.01$11,970,966.70
Jun 9, 2026

Pizzie Nick

Direct

Sell33.0K$240.09$7,922,970.00
Jun 2, 2026

Coleman Mark

Direct

Sell5.5K$223.39$1,236,910.43
Jun 1, 2026

Coleman Mark

Direct

Sell6.0K$230.30$1,381,800.00
May 29, 2026

Coleman Mark

Direct

Sell6.0K$233.46$1,400,760.00

1–10 of 52

Analysis

Insiders reported 3 buys worth $200,466.30 and 49 sells worth $146.09M over the last 12 months. That adds up to net selling of $145.89M. TABUTEAU HERRIOT was the most active insider with 17 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A14 analysts
RevenueN/AN/AN/A
N/A8 analysts
Net IncomeN/AN/AN/A
N/A8 analysts
EBITN/AN/AN/A
N/A8 analysts

Analysis

Analysis will appear once historical growth or forward estimates are available for this company.

Who manages AXSM?

Axsome Therapeutics, Inc. (AXSM) lists 6 active executives. The top listed executive is Ari Maizel, Chief Commercial Officer.

Are AXSM insiders buying or selling?

Recent insider activity shows net selling of $229.94M.

Explore More

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