Centessa Pharmaceuticals plc

Centessa Pharmaceuticals plc

Healthcare

NASDAQ:CNTA · NASDAQ Global Select

Market Cap $6.15B Beta 1.12 P/E (TTM) -24.3
$39.72 -0.13%

-$0.05 today

52W Low $12.05High $40.26

Vol 1.12M · Avg 2.59M

EPS (TTM)-$1.63
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-37.5%

avg -92.3%

ROIC

-32.2%

avg -50.1%

ROA

-28.7%

avg -44.6%

Analysis

ROA is currently the strongest return metric at -28.7% versus its period average of -44.6%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Mario Alberto Accardi

Chief Executive Officer & Director$1.23M40$243,282.000.16%

John J. Crowley

Chief Financial Officer$853,860.0052$181,000.000.12%

Stephen J. Kanes

Head of R&D and Chief Medical Officer$823,800.0061$120,000.000.08%

Iqbal J. Hussain

Chief Legal Officer, Chief Compliance Officer & Company Secretary$768,575.0045$160,000.000.10%

Gregory Weinhoff

Chief Business Officer$655,004.0055$89,923.000.06%

Charlene Stoudt

Senior Vice President of Clinical Development Operations

Raphael Deferiere

Senior VP & Chief Accounting Officer46$42,000.000.03%

Karen Anderson

Chief People Officer58$62,085.000.04%

Kristen K. Sheppard

Senior Vice President of Investor Relations & Corporate Communications

Tia L. Bush

Chief Technology & Quality Officer55$147,954.000.10%

Kimberly A. McCormick

Senior Vice President of Regulatory Affairs & Medical Writing

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

36

$19.13M

Net Sentiment

$19.13M

Net selling

Most Active

HUSSAIN IQBAL J

10 transactions

DateInsiderTypeSharesPriceValue
Mar 26, 2026

Weinhoff Gregory M

Direct

Sell24.0K$30.00$719,940.00
Mar 26, 2026

Anderson Karen M.

Direct

Sell41.1K$30.12$1,237,381.64
Mar 17, 2026

Anderson Karen M.

Direct

Sell10.0K$28.10$282,210.31
Mar 16, 2026

Anderson Karen M.

Direct

Sell64.8K$28.21$1,826,969.27
Mar 13, 2026

Anderson Karen M.

Direct

Sell108.0K$26.15$2,823,234.13
Mar 13, 2026

Anderson Karen M.

Direct

Sell12.1K$27.13$327,438.63
Mar 13, 2026

Weinhoff Gregory M

Direct

Sell61.3K$26.17$1,602,795.00
Mar 13, 2026

Weinhoff Gregory M

Direct

Sell11.9K$27.16$324,336.05
Feb 2, 2026

HUSSAIN IQBAL J

Direct

Sell39.0K$25.15$979,656.60
Jan 30, 2026

HUSSAIN IQBAL J

Direct

Sell1.0K$25.01$25,261.01

1–10 of 36

Analysis

Insiders reported 0 buys worth $0.00 and 36 sells worth $19.13M over the last 12 months. That adds up to net selling of $19.13M. HUSSAIN IQBAL J was the most active insider with 10 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A4 analysts
RevenueN/AN/AN/A
+101.6% (7yr)5 analysts
Net IncomeN/AN/AN/A
N/A5 analysts
EBITN/AN/AN/A
N/A5 analysts

Analysis

Forward estimates point to Revenue at +101.6% (7yr), giving you a quick read on expected growth from here.

Who manages CNTA?

Centessa Pharmaceuticals plc (CNTA) lists 11 active executives. The top listed executive is Charlene Stoudt, Senior Vice President of Clinical Development Operations.

Are CNTA insiders buying or selling?

Recent insider activity shows net buying of $44.32M.

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