Crinetics Pharmaceuticals, Inc.

Crinetics Pharmaceuticals, Inc.

Healthcare

NASDAQ:CRNX · NASDAQ Global Select

Market Cap $3.63B Beta 0.24 P/E (TTM) -7.2
$34.47 +2.80%

+$0.94 today

52W Low $25.83High $57.99

Vol 0.99M · Avg 1.20M

EPS (TTM)-$4.77
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-46.9%

avg -5.9%

ROIC

-48.9%

avg -41.2%

ROA

-41.0%

avg -37.3%

Analysis

ROA is currently the strongest return metric at -41.0% versus its period average of -37.3%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

R. Scott Struthers

Founder, President, Chief Executive Officer & Director$1.19M64$515,878.000.49%

Tobin C. Schilke

Chief Financial Officer$1.02M51$78,121.000.07%

Stephen F. Betz

Co-Founder & Chief Scientific Officer$755,150.0060$141,342.000.13%

Jeff E. Knight

Chief Development & Operating Officer$714,970.0054$190,452.000.18%

Alan S. Krasner

Chief Endocrinologist$653,924.0063$153,473.000.15%

Kea Lingo

Chief Information Officer

Kevin Capps

Head of Intellectual Property

Adriana Cabre

Chief Human Resources Officer

Gayathri Diwakar

Senior Director of Investor Relations

Chris Robillard

Chief Business Officer

Garlan Adams

Chief Legal Officer & Corporate Secretary

Robert Cuddihy

Senior Vice President of Medical Affairs

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

21

$8.51M

Net Sentiment

$8.51M

Net selling

Most Active

Pizzuti Dana

7 transactions

DateInsiderTypeSharesPriceValue
Apr 8, 2026

Knight Jeff E.

Direct

Sell85.2K$40.10$3,415,036.30
Mar 16, 2026

Knight Jeff E.

Direct

Sell6.0K$37.11$220,804.50
Mar 16, 2026

Knight Jeff E.

Direct

Sell4.0K$37.77$149,606.97
Mar 16, 2026

Betz Stephen F.

Direct

Sell6.4K$37.11$236,427.81
Mar 16, 2026

Betz Stephen F.

Direct

Sell4.2K$37.77$160,182.57
Mar 16, 2026

Struthers Richard Scott

Direct

Sell13.2K$37.11$489,703.56
Mar 16, 2026

Struthers Richard Scott

Direct

Sell8.8K$37.77$331,809.45
Mar 12, 2026

Vivaldi Coelho Rogerio

Direct

Sell4.5K$36.08$161,530.16
Mar 12, 2026

Vivaldi Coelho Rogerio

Direct

Sell523$36.77$19,230.71
Mar 3, 2026

Okey Stephanie

Direct

Sell3.0K$39.67$119,010.00

1–10 of 21

Analysis

Insiders reported 0 buys worth $0.00 and 21 sells worth $8.51M over the last 12 months. That adds up to net selling of $8.51M. Pizzuti Dana was the most active insider with 7 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A1 analysts
RevenueN/AN/A-67.4%
+171.8% (10yr)6 analysts
Net IncomeN/AN/AN/A
N/A6 analysts
EBITN/AN/AN/A
N/A6 analysts

Analysis

Recent growth has been strongest in Revenue at -67.4% over three years. Forward estimates point to Revenue at +171.8% (10yr), giving you a quick check on whether expectations are accelerating or cooling.

Who manages CRNX?

Crinetics Pharmaceuticals, Inc. (CRNX) lists 12 active executives. The top listed executive is Alan S. Krasner, Chief Endocrinologist.

Are CRNX insiders buying or selling?

Recent insider activity shows net buying of $16.53M.

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