Maze Therapeutics, Inc.

Maze Therapeutics, Inc.

Healthcare

NASDAQ:MAZE · NASDAQ Global Market

Market Cap $1.34B Beta 2.26 P/E (TTM) -10.6
$24.05 -0.17%

-$0.04 today

52W Low $9.83High $53.65

Vol 0.59M · Avg 0.86M

EPS (TTM)-$2.27
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-36.9%

avg -280.6%

ROIC

-37.7%

avg -65.2%

ROA

-33.0%

avg -57.1%

Analysis

ROA is currently the strongest return metric at -33.0% versus its period average of -57.1%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Jason V. Coloma

Chief Executive Officer & Director$1.09M50$344,897.000.62%

Harold S. Bernstein

President of Research & Development and Chief Medical Officer$874,583.0066$207,554.000.38%

Courtney J. Phillips

General Counsel & Corporate Secretary$354,780.0051$32,000.000.06%

Misbah Tahir

CFO & Principal Accounting Officer$304,940.0051$325,000.000.59%

Andrew Good

VP & Corporate Controller

Vipin Vijayakumar

Vice President of R&D Infrastructure and Operations

Winston Tse

Senior Vice President of Drug Discovery

Nazila Habibizad

Senior Vice President of Technical Operations & Supply Chain63

Maarten Hoek

Senior Vice President of Research

Matt Krause

Senior Vice President of Human Resources

Amy Bachrodt

Senior Vice President of Finance$33,833.000.06%

Susan Limb

Senior Vice President of Clinical Development

Atul Dandekar

Chief Strategy & Business Officer54$36,643.000.07%

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

51

$15.09M

Net Sentiment

$15.09M

Net selling

Most Active

Bernstein Harold

20 transactions

DateInsiderTypeSharesPriceValue
Jun 1, 2026

Coloma Jason V

Indirect

Sell6.1K$26.20$159,536.69
Jun 1, 2026

Coloma Jason V

Indirect

Sell553$26.24$14,511.38
Jun 1, 2026

Bernstein Harold

Direct

Sell13.3K$25.57$338,940.17
Jun 1, 2026

Bernstein Harold

Direct

Sell1.6K$26.36$42,172.16
May 29, 2026

Dandekar Atul

Direct

Sell7.5K$26.34$197,553.75
May 26, 2026

Coloma Jason V

Indirect

Sell25.6K$26.02$665,515.73
May 22, 2026

Coloma Jason V

Indirect

Sell4.5K$26.00$117,104.45
May 22, 2026

Coloma Jason V

Indirect

Sell2.5K$26.00$64,428.00
May 15, 2026

Coloma Jason V

Indirect

Sell1.8K$26.00$47,372.00
May 15, 2026

Coloma Jason V

Indirect

Sell116$26.00$3,016.00

1–10 of 51

Analysis

Insiders reported 0 buys worth $0.00 and 51 sells worth $15.09M over the last 12 months. That adds up to net selling of $15.09M. Bernstein Harold was the most active insider with 20 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A2 analysts
RevenueN/AN/AN/A
N/A4 analysts
Net IncomeN/AN/AN/A
N/A4 analysts
EBITN/AN/AN/A
N/A4 analysts

Analysis

Analysis will appear once historical growth or forward estimates are available for this company.

Who manages MAZE?

Maze Therapeutics, Inc. (MAZE) lists 13 active executives. The top listed executive is Misbah Tahir, CFO & Principal Accounting Officer.

Are MAZE insiders buying or selling?

Recent insider activity shows net buying of $6.37M.

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