Xeris Biopharma Holdings, Inc.

Xeris Biopharma Holdings, Inc.

Healthcare

NASDAQ:XERS · NASDAQ Global Select

Market Cap $1.20B Beta 0.90 P/E (TTM) 96.4
$6.79 -2.02%

-$0.14 today

52W Low $4.36High $10.08

Vol 1.63M · Avg 1.63M

EPS (TTM)$0.07
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

4.0%

avg -36.3%

ROIC

8.9%

avg -48.0%

ROA

0.1%

avg -42.5%

Analysis

ROIC is currently the strongest return metric at 8.9% versus its period average of -48.0%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

John Shannon

Chief Executive Officer & Director$1.36M64$707,276.000.41%

Kevin McCulloch

President & Chief Operating Officer$913,527.0062$1.78M1.03%

Beth Hecht

Chief Legal Officer & Corporate Secretary$817,367.0062$1.18M0.68%

Steven Pieper

Chief Financial Officer$796,183.0049$1.39M0.81%

Anh Nguyen

Chief Medical Officer$653,703.0051$395,023.000.23%

Kendal Korte

Senior Vice President of Human Resources

Brian Conner

SVP of Quality and Chief Compliance & Risk Officer

Allison Wey

Senior Vice President of Investor Relations & Corporate Communications

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

1

$109,475.00

Sells

23

$4.46M

Net Sentiment

$4.35M

Net selling

Most Active

Hecht Beth

9 transactions

DateInsiderTypeSharesPriceValue
Jun 4, 2026

HALKUFF DAWN

Direct

Sell20.0K$6.09$121,886.00
Jun 4, 2026

BORMANN-KENNEDY BARBARA-JEAN ANNE

Direct

Sell16.0K$6.09$97,507.20
Jun 4, 2026

JOHNSON JOHN

Direct

Sell15.0K$6.09$91,422.00
Jun 3, 2026

PERSKY MARLA

Direct

Sell15.5K$5.90$91,432.95
Jun 1, 2026

Hecht Beth

Direct

Sell16.7K$6.06$100,982.02
May 1, 2026

Hecht Beth

Direct

Sell16.7K$6.23$103,805.41
Apr 1, 2026

Hecht Beth

Direct

Sell16.7K$5.99$99,858.66
Mar 30, 2026

Brady James Aloysius

Direct

Sell10.8K$5.54$60,035.53
Mar 2, 2026

Hecht Beth

Direct

Sell100$7.06$706.00
Mar 2, 2026

Hecht Beth

Direct

Sell16.6K$6.24$103,379.74

1–10 of 24

Analysis

Insiders reported 1 buys worth $109,475.00 and 23 sells worth $4.46M over the last 12 months. That adds up to net selling of $4.35M. Hecht Beth was the most active insider with 9 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A2 analysts
RevenueN/AN/A+135.9%
+42.5% (10yr)3 analysts
Net IncomeN/AN/AN/A
N/A3 analysts
EBITN/AN/AN/A
N/A3 analysts

Analysis

Recent growth has been strongest in Revenue at +135.9% over three years. Forward estimates point to Revenue at +42.5% (10yr), giving you a quick check on whether expectations are accelerating or cooling.

Who manages XERS?

Xeris Biopharma Holdings, Inc. (XERS) lists 8 active executives. The top listed executive is Anh Nguyen, Chief Medical Officer.

Are XERS insiders buying or selling?

Recent insider activity shows net buying of $4.17M.

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